{"id":2360,"date":"2017-11-21T11:53:52","date_gmt":"2017-11-21T11:53:52","guid":{"rendered":"http:\/\/www.fusariumwilt.org\/?p=2360"},"modified":"2019-05-08T10:46:35","modified_gmt":"2019-05-08T10:46:35","slug":"world-first-panama-disease-resistant-cavendish-bananas","status":"publish","type":"post","link":"https:\/\/fusariumwilt.org\/index.php\/en\/2017\/11\/21\/world-first-panama-disease-resistant-cavendish-bananas\/","title":{"rendered":"World-first Panama disease-resistant Cavendish bananas"},"content":{"rendered":"\n\t\t<style type=\"text\/css\">\n\t\t\t#gallery-1 {\n\t\t\t\tmargin: auto;\n\t\t\t}\n\t\t\t#gallery-1 .gallery-item {\n\t\t\t\tfloat: left;\n\t\t\t\tmargin-top: 10px;\n\t\t\t\ttext-align: center;\n\t\t\t\twidth: 100%;\n\t\t\t}\n\t\t\t#gallery-1 img {\n\t\t\t\tborder: 2px solid #cfcfcf;\n\t\t\t}\n\t\t\t#gallery-1 .gallery-caption {\n\t\t\t\tmargin-left: 0;\n\t\t\t}\n\t\t\t\/* see gallery_shortcode() in wp-includes\/media.php *\/\n\t\t<\/style>\n\t\t<div id='gallery-1' class='gallery galleryid-2360 gallery-columns-1 gallery-size-full'><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<a href='https:\/\/fusariumwilt.org\/index.php\/en\/2017\/11\/21\/world-first-panama-disease-resistant-cavendish-bananas\/tr4-resistant-cavendish-2\/'><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"696\" src=\"https:\/\/fusariumwilt.org\/wp-content\/uploads\/2017\/11\/tr4-resistant-cavendish-1.jpg\" class=\"attachment-full size-full\" alt=\"News: cavendish banana that is resistant to Panama Disease\" aria-describedby=\"gallery-1-2369\" srcset=\"https:\/\/fusariumwilt.org\/wp-content\/uploads\/2017\/11\/tr4-resistant-cavendish-1.jpg 1000w, https:\/\/fusariumwilt.org\/wp-content\/uploads\/2017\/11\/tr4-resistant-cavendish-1-300x209.jpg 300w, https:\/\/fusariumwilt.org\/wp-content\/uploads\/2017\/11\/tr4-resistant-cavendish-1-768x535.jpg 768w, https:\/\/fusariumwilt.org\/wp-content\/uploads\/2017\/11\/tr4-resistant-cavendish-1-610x425.jpg 610w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/a>\n\t\t\t<\/dt>\n\t\t\t\t<dd class='wp-caption-text gallery-caption' id='gallery-1-2369'>\n\t\t\t\tDistinguished Prof James Dale, is developing a cavendish banana that is resistant to Panama Disease\n\t\t\t\t<\/dd><\/dl><br style=\"clear: both\" \/>\n\t\t<\/div>\n\n<p class=\"p1\"><span class=\"s1\"><b>Researchers from Queensland University of Technology in Brisbane, Australia, have designed genetically modified Cavendish bananas with resistance to the devastating soil-borne Panama disease. This disease is caused by the fungus Fusarium oxysporum f.sp. cubense Tropical race 4 (TR4) and also known as Fusarium wilt of banana. Scientists from Wageningen University &amp; Research in the Netherlands validated the field data.<\/b><\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">In the&nbsp;world\u2019s first field trial with genetically modified banana plants conducted in heavily TR4-infested soil, one Cavendish line transformed with a gene taken from a wild banana remained completely TR4 free, while three other lines showed robust resistance. The&nbsp;results have just been published in&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/s41467-017-01670-6\" target=\"_blank\" rel=\"noopener\"><span class=\"s2\"><i>Nature Communications<\/i><\/span><\/a>.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">The team cloned the so-called RGA2 gene from the wild progenitor of edible bananas,&nbsp;<i>Musaacuminata<\/i>&nbsp;ssp.&nbsp;<i>Malaccensis<\/i>, which has a remarkable resistance to TR4. One modified Cavendish line (RGA2-3) remained TR4-free for the three years of the trial. Three other lines modified with RGA2 showed strong resistance, with 20% or fewer plants exhibiting disease symptoms over a period of three years. In contrast, 67% to 100% of the control bananas were either dead or heavily TR4-infected after three years, including the Giant Cavendish somaclonal variant 218, currently heralded as being resistant to TR.4.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">Running from 2012 to 2015, the field trial was led by Distinguished Professor James Dale from Queensland University of Technology. It was conducted on a commercial banana plantation outside Humpty Doo in the Northern Territory in Australia previously affected by TR4. The soil was also heavily reinfested with disease for the trial.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\"><b>&#8220;Absolute breakthrough&#8221;<\/b><\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">The research team of Gert Kema, professor in tropical phytopathology at Wageningen University &amp; Research, partnered in the project. \u201cThe GM banana lines show that the activity of the RGA2 gene is strongly correlated with the level of resistance to TR4,\u201d comments Kema. \u201cThis is an absolute breakthrough as it concerns the first identified resistance gene to Fusarium wilt. However, this is only the start \u2013 some light at the end of the tunnel. The next step is to deploy the immense diversity in wild bananas to diversify the fruit and establish a resilient and sustainable banana production for all. In 2012, we determined that this banana species has valuable resistance to TR4 and Professor Dale\u2019s group has now confirmed this by cloning the underlying gene. Our role was to validate the fungal infections using the molecular techniques that we developed to detect and quantify TR4.\u201d<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">While Cavendish bananas have been found to also have this RGA2 gene naturally, it is not very active in susceptible plants. New research is looking at how to \u2018switch on\u2019 the gene in Cavendish bananas to make them TR4 resistant.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">The researchers have begun an expanded field trial on the same plantation, growing the four resistant RGA2 lines and newly developed lines of modified Grand Nain and Williams Cavendish varieties. They have the capacity to screen up to 9,000 plants for resistance and to determine yields and other important traits over the coming five years.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">The article,&nbsp;<i>Transgenic Cavendish bananas with resistance to Fusarium wilt tropical race 4,<\/i>&nbsp;can be accessed<a href=\"https:\/\/www.nature.com\/articles\/s41467-017-01670-6\" target=\"_blank\" rel=\"noopener\"><span class=\"s3\">&nbsp;here.<\/span><\/a><\/span><\/p>\n<p class=\"p4\"><span class=\"s1\">&nbsp;<\/span><\/p>\n<p class=\"p4\"><span class=\"s1\">For further information, please contact&nbsp;prof. Dr. Ir. Gert Kema tel 00 31 317 480632 or by e-mail: <a href=\"mailto:gert.kema@wur.nl\"><span class=\"s4\">gert.kema@wur.nl<\/span><\/a><\/span><\/p>\n<p class=\"p5\"><span class=\"s1\">&nbsp;<\/span><span class=\"s1\">Co-authors with Professor Dale are Professor Gert Kema, Fernando Garcia-Bastidas (Wageningen University &amp; Research, the Netherlands), Dr Anthony James (QUT), Dr Jean-Yves Paul (QUT), Dr Harjeet Khanna (Sugar Research Australia, formerly QUT), Mark Smith (Darwin Banana Farming Company), Dr Santy Peraza-Echeverria (CICY, Mexico, formerly QUT), Professor Peter Waterhouse (QUT), Distinguished Professor Kerrie Mengersen (QUT) and Professor Robert Harding (QUT).<\/span><\/p>\n<p><a href=\"http:\/\/www.fusariumwilt.org\/index.php\/en\/news-events\/\">Back to News page<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from Queensland University of Technology in Brisbane, Australia, have designed genetically modified Cavendish bananas with resistance to the devastating soil-borne Panama disease. This disease is caused by the fungus Fusarium oxysporum f.sp. cubense Tropical race 4 (TR4) and also known as Fusarium wilt of banana. Scientists from Wageningen University &amp; Research in the Netherlands [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"gallery","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_uf_show_specific_survey":0,"_uf_disable_surveys":false,"iawp_total_views":27,"footnotes":""},"categories":[29,31],"tags":[],"class_list":["post-2360","post","type-post","status-publish","format-gallery","hentry","category-publications","category-studies","post_format-post-format-gallery"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/posts\/2360","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/comments?post=2360"}],"version-history":[{"count":11,"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/posts\/2360\/revisions"}],"predecessor-version":[{"id":2884,"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/posts\/2360\/revisions\/2884"}],"wp:attachment":[{"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/media?parent=2360"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/categories?post=2360"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fusariumwilt.org\/index.php\/wp-json\/wp\/v2\/tags?post=2360"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}